|
Lactose Intolerance
Testing
Lactose intolerance is the
inability to digest significant amounts of lactose, the major sugar found in
milk. Lactose intolerance is caused by a shortage of the enzyme lactase,
which is produced by the cells that line the small intestine. Lactase breaks
down milk sugar into two simpler forms of sugar called glucose and
galactose, which are then absorbed into the bloodstream. Not all people
deficient in lactase have the symptoms commonly associated with lactose
intolerance, but those who do are said to have lactose intolerance.

Lactose intolerance can be hard to diagnose based on symptoms alone. People
sometimes think they suffer from lactose intolerance because they have the
symptoms associated with the disorder, not knowing other conditions such as
irritable bowel syndrome can cause similar symptoms. A doctor can use tests
to diagnose lactose intolerance but may first recommend eliminating cow’s
milk from the diet to see if the symptoms go away.
The Hydrogen Breath Test
This test measures the amount of hydrogen in
a person’s breath. Very little hydrogen is normally detectable. However,
undigested lactose in the colon is fermented by bacteria and produces
various gases, including hydrogen. The hydrogen is absorbed from the
intestines, carried through the bloodstream to the lungs, and exhaled. In
this test, the person drinks a lactose-loaded beverage and the breath is
analyzed at regular intervals. Raised levels of hydrogen in the breath
indicate improper digestion of lactose. Certain foods, medications, and
cigarettes can affect the accuracy of the test and should be avoided before
taking the test. People should check with their doctor to make sure they are
not taking medications that may interfere with test results.
Publications produced by the Clearinghouse are carefully reviewed by both
NIDDK scientists and outside experts. This publication was originally
reviewed by Eric Sibley, M.D., Ph.D., Stanford University School of
Medicine.
This publication is not copyrighted. The Clearinghouse encourages users of
this publication to duplicate and distribute as many copies as desired. |